scirpy.datasets.iedb

scirpy.datasets.iedb(cached=True, *, cache_path='data/iedb.h5ad')

Download IEBD v3 and process it into an AnnData object.

[VMO+19] is a curated database of T-cell receptor (TCR) sequences with known antigen specificities.

Parameters
cached : bool (default: True)

If True, attempt to read from the data directory before downloading

cache_path

Location where the h5ad object will be saved

Return type

AnnData

Returns

An anndata object containing all entries from IEDB in obsm["airr"]. Each entry is represented as if it was a cell, but without gene expression. Metadata is stored in adata.uns["DB"].